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UHR Brain PET Scanner

THE NEW STANDARD IN BRAIN PET IMAGING

Achieving the world's highest resolution, the UHR is a game changer for brain PET imaging, unleashing groundbreaking precision and clarity for transformative research.

UHR Brain PET Scanner

Accomplish More with the UHR Brain PET Scanner, Delivering Unparalleled Resolution

​Introducing the new UHR (Ultra-High-Resolution) Brain PET Scanner, setting a new gold standard in precision and clarity for brain imaging. With unrivaled spatial resolution and advanced capabilities, this cutting-edge technology empowers researchers and healthcare professionals to explore the complexity of the human brain like never before. 

Our True Pixel Detectors offer PET images with a spatial resolution better than 1.2 mm, a two-fold improvement over current standards, thanks to its LYSO-based pixelated detectors measuring 1.125 x 1.125 x 12 mm³. This technology enables high intrinsic resolution, high count rate capabilities with minimal dead time, and optimizes clinical outcomes, guaranteeing superior performance. 

Experience the future of healthcare innovation with the UHR scanner and unlock unprecedented insights into neurodegenerative diseases, brain cancer, mental health disorders, and more. 

 

  • True Pixel Detector Technology 

  • ​​Less Than 2 µL Isotropic Volumetric Spatial Resolution

  • ​​High Contrast Throughout the Entire Brain

  • ​​Flexible Real-Time Software Coincidence Engine

UHR Brain PET Scanner
The UHR LabPET II technology Detectors

The LabPET II detection unit is a 128-channel detector module based on four arrays of elementary unit. Each unit consists of 4×8 array of 1.125 × 1.125 × 12 mm³ LYSO (Lu1.9 Y0.1 SiO5) scintillator pixels individually coupled to a monolithic array of 4×8 avalanche photodiodes (APD). A custom electronic board acts as an interposer between the four arrays of detectors and two 64-channel, mixed-signal, Application Specific Integrated Circuit (ASIC) to form a 128-channel readout unit. 

The ASIC characterizes detected events with both timestamp and energy along with their pixel address. These features are extracted using a dual-threshold time-over-threshold (TOT) scheme, a technique based on the time an analog signal spends over fixed thresholds.  A DAQ system was designed to interface the ASICs and process PET data in real-time. The digitized data for each single event are transferred through gigabit internet links to the acquisition computer for coincidence processing and list mode data generation. 

  • The true pixelated detector module eliminates spatial distortion, which can considerably impair image quality. 

  • Using resolution phantoms, 1.0 mm rods can be resolved at the center of the field of view, and 1.2 mm/1.6 mm rods are resolved at radial positions of 5 cm and 10 mm, respectively.  

Next-Generation Performance Enhancement Systems

UHR Brain PET Scanner
UHR Brain PET Scanner
UHR Brain PET Scanner
UHR Brain PET Scanner

Elevating the User Experience with Comfort and Usability in Mind

Alleviating Stress by Design

With the UHR Scanner, we’ve added an array of new features to make the scan as relaxing as possible for patients. The system features LED ambient lighting to help create a calming mood as well as a gentle breeze on the inside area of the bore to help in both alleviating stress and reducing movement for nervous patients. These seemingly small details can have a huge impact on improving the user experience and scan quality.

User Friendly Interface

Featuring a uniquely streamlined interface, characterized by its simplicity and ease of use and designed with user convenience in mind, navigating the system is intuitive and straightforward. Our commitment to simplicity ensures that users can operate the scanner with ease, maximizing efficiency and minimizing learning curves. With our user-friendly interface, performing scans becomes a seamless and intuitive process.

Engineered for Comfort

Our UHR Scanner features a unique patient table designed with comfort and stability in mind. Unlike traditional whole-body scanners, our patient table is larger, accommodating a wider range of body types and ensuring  optimal comfort during extended sessions. Engineered for users to rest completely still for extended periods, the table's design maximizes the benefits of our scanner's unparalleled resolution. With a focus on user’s well-being and stability, our patient table sets a standard for comfort and performance in PET acquisitions.

Unveiling Rarely Seen Brain Regions with PET Imaging

​The benefits of ultra-high-resolution in PET brain imaging provide new insight into neurodegenerative diseases. 

Thanks to this quantum leap in image resolution, many regions of the brain, previously only visible in MRI images, such as the brainstem nuclei and regions of subcortical anatomy rarely seen as distinct entities, can now be discernible and quantifiable in UHR PET images.

This revolutionary advancement in resolution is paving the way for deeper insights into the pathophysiology of neurodegenerative disorders. By providing unprecedented detail and precision, UHR PET imaging empowers researchers and clinicians to unravel the complexities of brain function and dysfunction, offering new avenues to pursue new and existing research and ultimately, providing better outcomes.

Images taken on the new UHR Brain PET Scanner
Images taken on the new UHR Brain PET Scanner
Images taken on the new UHR Brain PET Scanner

Based on field-proven LabPET II detection technology 
Spatial resolution at the center of FOV: <1.20 mm 

Images taken on the new UHR Brain PET Scanner

Imaging of the brainstem with the UHR Brain PET Scanner

Potential for accurate in vivo quantification of brainstem nuclei of high interest such as the locus coeruleus and the raphe nuclei​
Identification of structures rarely or never observed before in FDG-PET
Microvolumetric resolution

Imaging of the brainstem with the UHR Brain PET Scanner

UHR Spatial Resolution with Mini Deluxe Phantom
UHR Spatial Resolution with Ultra-Micro Phantom

1.2 mm: Average V/P=0.67, 74% resolved 

UHR Spatial Resolution with Mini Deluxe Phantom

1.0 mm : Average V/P=0.63, 87% resolved 

UHR Spatial Resolution with Ultra-Micro Phantom

Hy: Hypothalamus;  IC: Inferior colliculi;  IF: Interpeduncular fossa;  MB: Mammillary bodies;
RN: Red nuclei;  SC: Superior colliculi;  STN Subthalamic nuclei 

Imaging of the Diencephalon & Midbrain with the UHR Scanner

Diencephalon & Midbrain

Imaging of the Thalamus with the UHR Scanner

Thalamus

Images taken on the Discovery MI PET/CT Scanner
Images taken on the new UHR Brain PET Scanner

4 mm /  64 µL

Discovery MI PET/CT Scanner

1.2 mm / 2 µL

NEW UHR Brain PET Scanner

The UHR Scanner Detectors with Christian

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