preclinical pet scanners

New Generation of Scanners

After the commercial success of the LabPET I (also known as “Triumph”, “LabPET 4”, “LabPET 8”, “LabPET 12” or “LabPETTM First Generation”), the improved second generation of LabPET scanners was officially launched in 2020. These preclinical imaging scanners are available as standalone, table-top or even as an integrated PET/CT system.

The challenges with preclinical small animal research is the scale at which measurements are made and being able to be cost-efficient with funding. For that, the LabPET II preclinical scanners offer ultra-high precision, which enables the exploration of new research challenges. With its modular approach, the LabPET II scanners offer 48 possible configurations, allowing it to be the best solution for every need and budget. The four available preclinical ring diameters allow preclinical imaging of mouse, rat, rabbit & mid-size animals. For each of the diameters, it is possible to choose a configuration between 1 and 12 rings for a wide range of single or multi-bed imaging studies.

Better spatial resolution can bring better & quicker results, making it possible for research groups to reduce experiment cycles & optimize the use of resources. In many cases, ultra-high precision can allow new possible studies or simply make the difference between being able or not to reach definitive conclusions.

Mouse

Rat

Rabbit

Mid-Size

12 rings configuration

12 rings configuration

12 rings configuration

12 rings configuration

Axial Field of View

Single bed position FOV

156mm

156mm

156mm

156mm

Total Axial Field of View

Multi-bed position FOV

300mm

300mm

> 600mm

> 750mm

Transaxial Field of View

Optimal transaxial FOV

60mm

90mm

125mm

180mm

Ring Diameter

Distance between detectors

80mm

119mm

160mm

260mm

Gantry Opening

Standalone open space

72mm

108mm

140mm

203mm

Sensitivity

Calculated at center

> 6,2%

> 3,6%

> 2,9%

> 2,2%

LYSO Crystal Size

1.12 x 1.12 x 12mm3 4x8 Arrays

Number of Detection Modules

144

216

288

432

Total Number of Crystals

18 432

27 648

36 864

55 296

Spatial Resolution

True resolution calculated at center without CT, digital or coding

< 0,75mm

< 0,85mm

< 0,95mm

< 1mm

Note : All numbers may vary if standalone, tabletop or PET/CT integration is chosen.

COMPARE THE LabPET 1ST & 2ND GENERATION

LabPET I

Also known as Triumph, LabPET 4-8-12, LabPETTM

LabPET II

Here showing mouse 4 rings configuration performances

Spatial Resolution

@ 5mm from center

1,65mm

0,76mm

Sensitivity

[250-650keV]

1,42%

3,3%

Uniformity

6,0%

8,2%

Recovery Coefficient

Down to 3mm

Down to 2mm

Spill Over Ratio

[air/water] (%)

24 / 16

31 / 20

The table above shows the published NEMA comparison of the LabPET I and the LabPET II 4-rings mouse configuration performances. Compared to the previous generation, the LabPETTM, this detector module offers a ∼5.6-fold and ∼1.7-fold increase respectively in acquisition channel density and count rates per cm2. This is shown in the performance displayed in the table above, especially with the spatial resolution at the center of the scanner. 

LABPET II PRECLINICAL SCANNERS

High precision

Modularity

Reliability